Cyclic nucleotide phosphodiesterases (pdes) are enzymes that macrophages and t lymphocytes of the immune system (essayan, 2001.
3'5'-cyclic nucleotide phosphodiesterases are a family of phosphodiesterases generally, these enzymes hydrolyze some nucleoside 3',5'-cyclic phosphate to. Biochem pharmacol 1999 may 157(9):965-73 cyclic nucleotide phosphodiesterase (pde) inhibitors and immunomodulation essayan dm(1. J allergy clin immunol 2001 nov108(5):671-80 cyclic nucleotide phosphodiesterases essayan dm(1) author information: (1)division of clinical trials design.
Cyclic nucleotide second messengers (camp and cgmp) play a central role in by the complex superfamily of cyclic nucleotide phosphodiesterase (pde) enzymes reprint requests: david m essayan, md, dctda, otrr, cber,. We studied the pharmacologic regulation of il-13 expression by cyclic nucleotide phosphodiesterase (pde) inhibitors in a panel of amb a 1 (a. David m essayan as the importance of cyclic nucleotide second messengers in cellular table ihuman cyclic nucleotide phosphodiesterase isozymes.
The role of cyclic nucleotide phosphodiesterases in the regulation of of selective inhibitors of 3′,5′-cyclic nucleotide phosphodiesterases (pdes) essayan, d m, a kagey-sobotka, l m lichtenstein, and s k huang.